This comic is Rhymes with Orange by Hilary B. Price. “Hilary” is descended from the Greek word for “laughter,” by the way. It’s funny to me because of how she misused “misplaced.”
I notice the title of the strip is plural, and she seems to be as bothered by the comma as Arnold is.
Okay, I can’t resist. Here are some more words that don’t have rhymes in English: purple, month, scarce, scarf, coif,fugue, gulf, and false.